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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HIRA
All Species:
19.39
Human Site:
T542
Identified Species:
26.67
UniProt:
P54198
Number Species:
16
Phosphosite Substitution
Charge Score:
0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P54198
NP_003316.3
1017
111835
T542
N
K
D
S
M
N
A
T
S
T
P
A
A
L
S
Chimpanzee
Pan troglodytes
XP_001165585
1017
111787
T542
N
K
D
S
M
N
A
T
S
T
P
A
A
L
S
Rhesus Macaque
Macaca mulatta
XP_001112873
1138
124408
T663
N
K
D
S
M
N
A
T
S
T
P
A
A
L
S
Dog
Lupus familis
XP_543550
1017
111618
T542
S
K
D
S
V
N
A
T
S
T
P
A
A
S
S
Cat
Felis silvestris
Mouse
Mus musculus
Q61666
1015
111748
S542
K
D
S
M
N
A
T
S
T
P
A
A
S
S
P
Rat
Rattus norvegicus
NP_001129232
1015
111665
S542
K
D
S
M
N
A
T
S
T
P
A
A
L
S
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
P79987
1019
112055
V542
D
A
A
S
K
D
G
V
N
A
T
S
V
S
T
Frog
Xenopus laevis
Q8QFR2
1013
112021
S542
K
E
S
G
N
V
S
S
S
S
P
V
A
P
T
Zebra Danio
Brachydanio rerio
XP_696478
1010
111223
K542
P
V
N
S
I
G
M
K
S
T
L
L
L
T
S
Tiger Blowfish
Takifugu rubipres
O42611
1025
111838
V542
L
E
D
N
K
D
G
V
K
S
C
L
L
L
T
Fruit Fly
Dros. melanogaster
O17468
1047
113397
H539
R
T
P
R
L
E
E
H
Q
S
S
T
C
S
P
Honey Bee
Apis mellifera
XP_001122939
838
91355
E388
C
T
V
M
E
A
P
E
L
L
N
L
K
T
S
Nematode Worm
Caenorhab. elegans
Q09589
935
103412
D485
F
C
G
T
T
T
A
D
P
M
T
S
L
S
S
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Q32SG6
964
105548
P514
P
N
H
S
Q
N
H
P
V
N
F
S
S
L
D
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9LXN4
1051
115544
E542
C
R
N
P
D
L
K
E
R
S
R
I
T
A
R
Baker's Yeast
Sacchar. cerevisiae
P32479
840
93871
L390
F
K
F
E
N
N
E
L
G
K
P
I
P
L
E
Red Bread Mold
Neurospora crassa
Q7RZI0
1035
112420
S540
P
Q
T
I
L
D
L
S
K
P
Y
D
G
L
P
Conservation
Percent
Protein Identity:
100
99.9
88.4
96.5
N.A.
95.7
95.5
N.A.
N.A.
86
78
69.8
67.7
31.1
40
26.5
N.A.
Protein Similarity:
100
99.9
88.9
98
N.A.
97.5
97.7
N.A.
N.A.
93.1
88.5
83.2
81.3
48
55.1
46.1
N.A.
P-Site Identity:
100
100
100
80
N.A.
6.6
6.6
N.A.
N.A.
6.6
20
26.6
13.3
0
6.6
13.3
N.A.
P-Site Similarity:
100
100
100
93.3
N.A.
26.6
20
N.A.
N.A.
40
53.3
40
46.6
13.3
6.6
26.6
N.A.
Percent
Protein Identity:
N.A.
25.6
N.A.
25
22.4
25.9
Protein Similarity:
N.A.
43.7
N.A.
43.3
41.2
45.8
P-Site Identity:
N.A.
20
N.A.
0
26.6
6.6
P-Site Similarity:
N.A.
33.3
N.A.
20
26.6
33.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
6
6
0
0
18
30
0
0
6
12
36
30
6
0
% A
% Cys:
12
6
0
0
0
0
0
0
0
0
6
0
6
0
0
% C
% Asp:
6
12
30
0
6
18
0
6
0
0
0
6
0
0
6
% D
% Glu:
0
12
0
6
6
6
12
12
0
0
0
0
0
0
6
% E
% Phe:
12
0
6
0
0
0
0
0
0
0
6
0
0
0
0
% F
% Gly:
0
0
6
6
0
6
12
0
6
0
0
0
6
0
0
% G
% His:
0
0
6
0
0
0
6
6
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
6
6
0
0
0
0
0
0
12
0
0
0
% I
% Lys:
18
30
0
0
12
0
6
6
12
6
0
0
6
0
0
% K
% Leu:
6
0
0
0
12
6
6
6
6
6
6
18
24
42
0
% L
% Met:
0
0
0
18
18
0
6
0
0
6
0
0
0
0
0
% M
% Asn:
18
6
12
6
24
36
0
0
6
6
6
0
0
0
0
% N
% Pro:
18
0
6
6
0
0
6
6
6
18
36
0
6
6
24
% P
% Gln:
0
6
0
0
6
0
0
0
6
0
0
0
0
0
0
% Q
% Arg:
6
6
0
6
0
0
0
0
6
0
6
0
0
0
6
% R
% Ser:
6
0
18
42
0
0
6
24
36
24
6
18
12
36
42
% S
% Thr:
0
12
6
6
6
6
12
24
12
30
12
6
6
12
18
% T
% Val:
0
6
6
0
6
6
0
12
6
0
0
6
6
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
6
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _